<\/a>Helen
Taussig, taken during her time as a professor at Johns Hopkins
University.<\/p><\/div>Prior to 1944, children born with a condition known
as Tetralogy of
Fallot<\/a> – or more commonly \u201cblue baby syndrome\u201d
– could expect poor physical development, difficulty feeding, and an
early death (untreated cases saw only 30% survive to the age of 10).
Tetralogy of Fallot was the most common (400 cases out of every million
live births) of complex heart defects and considered at the time to be
surgically irreparable.<\/p>\n
Taussig (b. 1898) had other ideas. Having studied at a series of
prestigious schools, including Harvard, Taussig graduated from Johns
Hopkins University Medical School in 1927, moving to Johns Hopkins
Hospital to spend several years specialising in cardiology and
paediatrics. In 1930 she was appointed head of the Children\u2019s Heart
Clinic, making her one of the highest ranking women in American medicine
at the time. She noted that infants with another particular heart
deformity (patent ductus arteriosus, which allows blood to flow between
the aorta and the pulmonary artery) who suffered from Tetralogy of Fallot
tended to have better survivability than those with Tetralogy of Fallot
alone.<\/p>\n
Based on this, Taussig came to a conclusion that had evaded everyone else
up until then: by creating an artificial hole, or shunt, between the two
arteries it might be possible to overcome most of the problems caused by
Tetralogy of Fallot. She took her ideas to Robert Gross, a surgeon at
Boston who had pioneered patent ductus arteriosus ligation (the tying off
of the hole between the arteries to stop the flow between them). Gross
dismissed the idea, acting on the accepted wisdom of the time that stated
the condition to be impossible to fix surgically. Without the help of an
experienced cardiac surgeon, there would be no way to actually test
Taussig\u2019s ideas.<\/p>\n
In addition to the resistance from established surgeons, Taussig faced
another obstacle to developing her idea: Around the time of graduating
from Johns Hopkins she had become profoundly deaf, something which seemed,
at the time, like it might put an end to her career. How could one
practise cardiology without being able to hear heart rhythms through a
stethoscope? Taussig was not one to be stopped by such trifling matters
though, and developed an exceptional proficiency for feeling the rhythms
by hand instead of listening to them, later crediting some of her
discoveries to this talent.<\/p>\n
You must learn to listen with your fingers.<\/p>\n
\u2013 Dr Helen Taussig<\/p><\/blockquote>\n
This might be the point where a less awesome individual might give up,
might let their idea drop and become just another footnote in medical
history. Instead, Taussig approached Alfred Blalock, a recent
appointment at Johns Hopkins Hospital. Together with his surgical
technician, Vivien Thomas, they began to develop the idea, and by 1944
were ready to perform their first operation on a person.<\/p>\n
The first operation was a qualified success – the initial surgery
went well, but the patient didn\u2019t survive a follow up surgery the
following year. The following two attempts were wholly successful, and
by 1952 over 1,000 patients had undergone the Blalock-Taussig Shunt
procedure, as it became known, with around 85% survival rates. Taussig
and Blalock lectured on their technique in Paris and London, where
surgeons experienced similar success rates.<\/p>\n
But pioneering a new field of medicine and improving the life expectancy
and quality of life for countless infants wasn\u2019t enough for Taussig
– she had more awesome achievements still to go. In 1957 the
sedative drug Thalidomide<\/a>
was distributed to thousands of clinicians in the US for testing,
proposed as a safe drug for a variety of conditions. We now know, of
course, that the drug was far from safe for this, having massively
teratogenic properties. Taussig was one of the doctors, along with the
FDA inspector Frances
Oldham Kelsey<\/a>, who provided evidence for the dangers of the drug.
This lead to its being refused approval for sale in the US, and
eventually removed from other markets once its dangers had been
exposed.<\/p>\n
So that\u2019s twice that Taussig was a key figure in improving the
quality of life of infants, thus arguably making the world a better
place through her actions. In addition to this she campaigned for the
legalisation of abortion and became one of the first women to be
appointed to a full professorship at Johns Hopkins University in 1959,
and the first to serve as president of the American Heart Association.
One of the four colleges of the Johns Hopkins medical school still bears
her name.<\/p>\n
Her 1947 textbook,
Congenital Malformations of the Heart<\/strong>, is worth reading
whether or not one has a medical background, as it stands as an
example of a very well written work by one of the field\u2019s most
incisive minds.<\/p>\n
[Taussig] was truly a remarkably notable woman in health
care.<\/p>\n
– Harold Ellis,
Journal of Perioperative
Practice<\/strong><\/p><\/blockquote>\n